TABLE 3.
Intracellular Ca2+ fluorescence in C. albicans after BBH and FLC treatment.
CA 0253 | Time of drug action |
||
0 h | 2 h | 3 h | |
BBH + FLC◆★▲ | 4364.70 ± 44.33 | 5623.23 ± 41.16 | 5492.60 ± 11.00 |
FLC★△ | 3389.07 ± 4.18 | 4793.57 ± 9.49 | 4679.17 ± 24.69 |
BBH▲ | 4158.93 ± 53.24 | 5266.37 ± 14.98 | 5080.40 ± 16.00 |
Control | 3169.30 ± 54.53 | 4773.53 ± 45.29 | 4736.17 ± 16.4 |
CA 0253 were treated with BBH (2 μg/mL) plus FLC (1 μg/mL), FLC (1 μg/mL), BBH (2 μg/mL), and RPMI-1640 medium. Fluorescence was measured (emission: 530 nm) at 0, 2, and 3 h. Three independent experiments were performed, with eight replicates in each group (n = 8). Values represent means ± SEM. ANOVA tested statistical differences. ◆ compared with the FLC group, p < 0.05; ★ compared with the BBH group, p < 0.05; ▲compared with the control group, p < 0.05; Δ compared with the control group, p > 0.05.