Table 2.
Analytical performance of cobas® Liat® POCT on frozen samples using the Expanded Gold Standard (EGS) as reference
| TP | FP | FN | TN | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | |
|---|---|---|---|---|---|---|---|---|
| cobas® Liat® influenza A | 310 | 8 | 0 | 418 | 100% (99.0–100%) | 98.1% (96.3–99.0%) | 97.5% (95.1–98.7%) | 100% (99.0–100%) |
| cobas® Liat® influenza B | 163 | 2 | 0 | 571 | 100% (97.7–100%) | 99.7% (98.7–99.9%) | 98.8% (95.7–99.7%) | 100% (99.3–100%) |
| cobas® Liat® RSV | 26 | 4 | 0 | 706 | 100% (87.1–100%) | 99.4% (98.6–99.8%) | 86.7% (70.3–94.7%) | 100% (99.5–100%) |
TP true positives, FP false positives, FN false negatives, TN true negatives, 95% CI 95% confidence intervals, PPV positive predictive value, NPV negative predictive value