Fig. 2.

In vivo MR/BL imaging provides evidence of macrophage delivery to the kidneys, but no clear differences between injured (left) and healthy (right) kidney. a MRI of the kidneys at baseline and up to 2 days post administration of 5 × 10⁶ cells to SCID mice with an ischemia/reperfusion injury. On the cell administration day (day 0), hypointense contrast is seen in the cortices of the kidneys, indicating cell delivery. The contrast is lost in subsequent days. b T₂^* relaxation time of the kidney cortices and livers. Time points that do not share the same letters are significantly different from one another, p < 0.05 (Tukey’s post hoc test). p values for all comparisons are shown in SI Table 2. c BLI on cell administration day (day 0) shows whole-body distribution of cells, including the kidneys but the signal changes progressively in subsequent days, and by day 2, the signal is predominately found in the liver (dashed area) and spine