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. 2020 Jan 28;22(4):969–978. doi: 10.1007/s11307-020-01472-1

Table 2.

Logan plot (reversible uptake model) result summary

Region of interest (n = 6) AB distribution volume (ml) PC distribution volume (ml)
Flank tumor 1.13 ± 0.09 1.96 ± 0.15
Flank muscle 0.77 ± 0.13 1.38 ± 0.23
Neck tumor 1.21 ± 0.08 2.08 ± 0.13
Bone (femoral condyle) 5.11 ± 2.19 13.47 ± 7.70

AB, arterial blood radioactivity used as input; PC, plasma-corrected (population-based metabolite-corrected fraction of the arterial blood radioactivity) used as input

Paired student’s t tests comparing distribution volume of tumors versus flank muscle (both AB and PC) and comparing AB inputs versus PC inputs were all significant (p < 0.003 and p < 0.00004, respectively)