Table 2.

Surgical outcomes and costs among 462 surgically treated patients with a pituitary tumor stratified according to cohort

	Fast-track (N = 79)	Non-fast-track (N = 76)	p value*	Total (N = 155)	Historic cohort (N = 307)	p value**
Length of stay, mean (SD)	3.0 (1.9)	7.6 (8.6)	<0.001	5.3 (6.6)	5.7 (4.9)	0.363
Complications
Number of readmitted patients, N (%)	13 (16.5)	14 (18.4)	0.747	27 (17.2)	31 (10.1)	0.025
Length of stay of all readmissions, mean (SD)	3.6 (2.7)	4.3 (4.2)	0.647	4.0 (3.5)	4.1 (3.4)	0.917
Any complication, N (%)	38 (48.1)	46 (60.5)	0.147	84 (54.2)	179 (58.3)	0.427
Transient DI, N (%)	20 (25.3)	28 (36.8)	0.165	48 (31.0)	53 (17.3)	0.001
Permanent DI, N (%)	3 (3.8)	7 (9.2)	0.204	10 (6.5)	17 (5.5)	0.834
Delayed hyponatremia, N (%)	9 (11.4)	14 (18.4)	0.262	23 (14.8)	31 (10.1)	0.167
New onset pituitary deficiency, N (%)	4 (5.1)	9 (11.8)	0.148	13 (8.4)	22 (7.2)	0.709
Postoperative CSF leak, N (%)	3 (3.8)	8 (10.5)	0.126	11 (7.1)	25 (8.2)	0.719
Epistaxis, N (%)	10 (12.7)	2 (2.6)	0.032	12 (7.7)	29 (9.4)	0.606
Postoperative intracranial hemorrhage, N (%)	0 (0.0)	1 (1.3)	0.490	1 (0.6)	3 (1.0)	1.000
Hospital costs (in euro’s)
Admission, mean (SD)	7249 (1318)	10394 (5868)	<0.001	8791 (4488)	9127 (3306)	0.363
Readmission, mean (SD)	438 (1221)	608 (1759)	0.486	521 (1506)	323 (1287)	0.141
Emergency room visits, mean (SD)	42 (108)	50 (153)	0.677	46 (132)	25 (85)	0.039
Outpatient clinic visits, mean (SD)	55 (102)	332 (68)	<0.001	191 (164)	343 (34)	<0.001
E-mail contacts, mean (SD)	626 (284)	0 (0)	<0.001	319 (373)	0 (0)	<0.001
Telephone contacts, mean (SD)	242 (184)	0 (0)	<0.001	123 (178)	0 (0)	<0.001
Total hospital costs, mean (SD)	8652 (1748)	11,384 (5974)	<0.001	9992 (4562)	9818 (3488)	0.649

N number, SD standard deviation, IQR interquartile range, DI diabetes insipidus, CSF cerebrospinal fluid

Bold values indicate statistical significance p < 0.05

*Fast-track vs. non-fast-track; **Total vs. historic cohort