Table 1.
Other small molecules with in vitro activity against SARS-Cov-2.
| No. | Name | Structure | EC50 or IC50 (μM) | SI | Ref. |
|---|---|---|---|---|---|
| 1 | Abiraterone acetate |
|
1.94 | 47.6 | (Yuan et al., 2020) |
| 2 | ALLM |
|
2.07 | 48.3 | (Ma et al., 2020) |
| 3 | Amodiaquine |
|
4.20 | >7.1 | (Ianevski et al., 2020) |
| 4 | Auranofin |
|
1.40 | 4.1 | (Rothan et al., 2020) |
| 5 | Azithromycin |
|
2.12 | 19.0 | (Touret et al., 2020) |
| 6 | Baicalein |
|
12.5-25.0 | 2.0 | (Liu et al., 2020) |
| 7 | Baicalin |
|
10.27 | 19.0 | (Su et al., 2020) |
| 8 | Boceprevir |
|
1.90 | 52.6 | (Ma et al., 2020) |
| 9 | Carmofur |
|
24.30 | 5.4 | (Jin et al., 2020) |
| 10 | Cinanserin |
|
20.61 | 9.7 | (Jin et al., 2020) |
| 11 | CVL218 |
|
5.12 | 17.8 | (Ge et al., 2020) |
| 12 | Digitoxin |
|
0.23 | 214.1 | (Jeon et al., 2020) |
| 13 | Digoxin |
|
0.19 | 256.6 | (Jeon et al., 2020) |
| 14 | Diiodohydroxyquinoline |
|
1.38 | >72.5 | (Ianevski et al., 2020) |
| 15 | Ebselen |
|
4.67 | – | (Jin et al., 2020) |
| 16 | Fluspirilene |
|
3.16 | 9.6 | (Weston et al., 2020) |
| 17 | GC-376 |
|
3.37 | 29.7 | (Ma et al., 2020) |
| 18 | Hexachlorophene |
|
0.90 | 21.6 | (Jeon et al., 2020) |
| 19 | MDL28170 |
|
0.49 | 204.0 | (Ma et al., 2020) |
| 20 | Nafamostat |
|
0.0022 | 11363 | (Ko et al., 2020) |
| 21 | Nelfinavir |
|
0.77 | 83.1 | (Ohashi et al., 2020) |
| 22 | Niclosamide |
|
0.28 | 176.7 | (Jeon et al., 2020) |
| 23 | Ouabain |
|
0.097 | 515.5 | (Jeon et al., 2020) |
| 24 | Salinomycin sodium |
|
0.24 | 211.0 | (Jeon et al., 2020) |
| 25 | S312 |
|
1.55 | >64.6 | (Xiong et al., 2020) |
| 26 | S416 |
|
0.017 | >5882 | (Xiong et al., 2020) |