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Diagnostic performance of mNGS assay compared to conventional methods for CNS infections.
| Statistics | Metaphlan2 | IDseq |
|---|---|---|
| Total number of results | 74 | 74 |
| True positive | 11 | 18 |
| True negative | 53 | 53 |
| False positive | 2 | 3 |
| False negative | 8 | 0 |
| Sensitivity | 58% (95% CI 34–80%) | 100% (95% CI 81–100%) |
| Specificity | 96% (95% CI 87–100%) | 95% (94% CI 85–99%) |
| Accuracy | 86% (95% CI 77–93%) | 96% (95% CI 87–99%) |
