Table 3.
Variables | Expression of DAXX in cytoplasm | P value | Expression of DAXX in nuclear | P value | ||
---|---|---|---|---|---|---|
High (n = 147) | Low (n = 176) | High (n = 183) | Low (n = 140) | |||
Gender, n (%) | 0.412 | 0.188 | ||||
Male | 108 | 122 | 125 | 105 | ||
Female | 39 | 54 | 58 | 35 | ||
Age (years), n (%) | 0.917 | 0.727 | ||||
<60 | 68 | 83 | 84 | 67 | ||
≥60 | 78 | 93 | 99 | 73 | ||
Tumor size (cm), n (%) | 0.272 | 0.238 | ||||
<4 | 75 | 79 | 82 | 72 | ||
≥4 | 73 | 97 | 101 | 68 | ||
Depth of invasion, n (%) | 0.105 | 0.602 | ||||
T1 + T2 | 56 | 52 | 59 | 49 | ||
T3 + T4 | 91 | 124 | 124 | 91 | ||
Lymph node metastasis, n (%) | <0.01a | 0.561 | ||||
N0 + N1 | 94 | 80 | 96 | 78 | ||
N2 + N3 | 53 | 96 | 87 | 62 | ||
M stage | 0.599 | 0.680 | ||||
M0 | 145 | 171 | 178 | 138 | ||
M1 | 2 | 5 | 5 | 2 | ||
TNM stage | 0.003a | 0.407 | ||||
I + II | 83 | 70 | 83 | 70 | ||
III + IV | 64 | 106 | 100 | 70 | ||
Lauren type | <0.01a | 0.540 | ||||
Intestinal | 85 | 61 | 80 | 66 | ||
Diffuse | 62 | 115 | 103 | 74 | ||
CEA | 8.40 ± 21.60 | 6.50 ± 21.83 | 0.449 | 8.26 ± 22.95 | 6.09 ± 19.78 | 0.394 |
CA199 | 36.64 ± 88.87 | 55.28 ± 159.17 | 0.219 | 53.43 ± 150.50 | 36.27 ± 95.15 | 0.286 |
CA724 | 7.22 ± 15.93 | 16.89 ± 47.37 | 0.047 | 13.69 ± 36.15 | 9.77 ± 36.98 | 0.465 |
Chemotherapy | 0.261 | 0.173 | ||||
No | 45 | 44 | 45 | 44 | ||
Yes | 102 | 132 | 138 | 96 | ||
Borrmann | 0.438 | 0.203 | ||||
I | 18 | 13 | 14 | 17 | ||
II | 57 | 74 | 69 | 62 | ||
III | 62 | 73 | 83 | 52 | ||
IV | 10 | 16 | 17 | 9 | ||
Relapse | <0.01a | <0.01a | ||||
No | 105 | 74 | 81 | 98 | ||
Yes | 42 | 102 | 102 | 42 |
CEA carcinoembryonic antigen, CA199 carbohydrate antigen199, CA724 carbohydrate antigen724, TNM tumor node and metastasis.
aStatistically significant (P < 0.01).