Table 2.

Univariate and multivariate analyses of SNHG12 mRNA level and patient survival.

Variables	Univariate analysis			Multivariate analysisc
	HRa	95% CIb	P value	HR	95% CI	P value
Overall survival (n = 500)
SNHG12 low (n = 250) high (n = 250)	2.021	1.449–2.819	0.000	1.510	1.060–2.152	0.022
Age (years) <60 (n = 233) ≥60 (n = 267)	2.011	1.429–2.829	0.000	1.807	1.277–2.555	0.001
Gender female (n = 173) male (n = 327)	0.962	0.689–1.343	0.821	–	–	–
T stage T1 or T2 (n = 339) T3 or T4 (n = 161)	2.963	2.147–4.088	0.000	1.660	1.156–2.384	0.006
N stage N0 or NX (n = 488) N1 (n = 12)	3.184	1.558–6.504	0.001	1.520	0.724–3.192	0.268
M stage M0 or MX (n = 447) M1 (n = 53)	4.855	3.410–6.912	0.000	2.961	1.990–4.404	0.000
G grade G1 or G2 or GX (n = 246) G3 or G4 (n = 254)	2.562	1.797–3.651	0.000	1.806	1.246–2.620	0.002

^aHazard ratio, estimated from Cox proportional hazard regression model.

^bConfidence interval of the estimated HR.

^cMultivariate models were adjusted for T, N, M classification, age and gender.