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. 2020 Jul 2;11:632. doi: 10.3389/fphys.2020.00632

Table 4.

Severity of CP.

References Distribution of CP Level of impairment of functional mobility
Total N Walk-DMC Total N Walk-DMC Structure
Tang et al. (2015) Uni: 4 both legs
Bi: 2 or 3 per leg
- GMFCS I: 2 = 50%;
3 = 25%; 4 = 25%
GMFCS II: 2 = 50%;
3 = 17%; 4 = 33%
GMFCS III: 2 = 25%;
3 = 75% GMFCS IV: 2 = 100%
- -
Steele et al. (2015) - He: 89.2 (87.8–90.6)
Di: 86.9 (85.9–87.9)
Tri: 84.4 (82.5–86.3)
Quad: 81.4 (80.0–82.8)
- GMFCS I: 92.4 (91.1–93.7)
GMFCS IV: 79.2 (77.5–80.9)
FAQ = 10: 90.9 (89.2–92.6)
FAQ <7: 80.0 (78.7–81.3)
Higher GMFCS level = more synergy structures that are specific to CP
Yu et al. (2019) - - GMFCS I/II = 4;
GMFCS III = 3
- GMFCS I: DAM = 29.8;
GMFCS II: DAM = 30.6;
TD: DAM = 26.4
Hashiguchi et al. (2018) - - No correlation with
GMFCS levels:
χ2 = 4.06, p = 0.40
- -
Kim Y. et al. (2018) - - No correlation with GMFCS levels - GMFCS level was correlated with normalized cluster number:
r = 0.51, p = 0.01

CP, cerebral palsy; N, number of synergies; Walk-DMC, dynamic motor control index during walking; Uni, unilateral; Bi, bilateral; He, hemiplegic; Di, diplegic; Tri, triplegic; Quad, quadriplegic; GMFCS, gross motor function classification system; DAM, deviation of activation matrix (to identify variability of activations patterns between subjects).