Table 2.

Experimental task results and demographic and clinical variables for patients with postoperative hypothalamic lesions (HL) and controls participating in the Identification of Emotional Expressions.

Identification of Emotional Expressions
	All patientsa	Patients with postop HL	All controls	All patients vs. all controls (p-value)	Patients with HL vs. all controls (p-value)
Task Performance
n	16	12	29
Single emotions	0.38 (0.12)	0.35 (0.12)	0.43 (0.11)	0.045*	0.039*
Family accuracy score	0.525 (0.13)	0.515 (0.11)	0.6 (0.11)	0.061	0.039*
Family accuracy score (negative items)	0.563 (0.16)	0.517 (0.13)	0.567 (0.13)	0.075	0.046*
Family accuracy score (positive items)	0.563 (0.16)	0.563 (0.14)	0.625 (0.14)	0.224	0.216
Demographic and Clinical Variables
n	16	12	29
% Female gender	56.3	75	62.1	0.758	0.507
Age at study (years)	22.5 (14) range: 13–38	22.5 (16) range: 13–38	24 (12) range: 12–40	0.766	0.989
Age at diagnosis (years)	10.9 (5.9)	10.9 (5.6)	–	–	–
BMI SDS	4.5 (7.2)	5.1 (6.4)	0.42 (1.5)	<0.001***	<0.001***
% Radiation therapy	50	50	–	–	–
n Baseline OSC	15	11	26
Baseline OSC	3.7 (3)	3.7 (3.1)	4.6 (9.1)	0.336	0.349
n BDI-II	14	11	29
BDI-II (raw scores)	6 (12)	12 (10)	4 (5)	0.231	0.04*
n STAI State	14	11	28
STAI State (raw scores)	35.5 (11)	37 (12)	31 (6)	0.004**	0.007**
STAI Trait (raw scores)	40 (17)	43 (10)	35.5 (9)	0.177	0.034*

For the experimental task, the proportion of correctly matched emotions/emotion categories is depicted and the primary measure is highlighted in bold. Medians and interquartile ranges (in brackets) are shown, unless otherwise specified. With the exception of gender where we used the χ2- test, all analyses were performed with the Mann-Whitney U–test.

^*p < 0.05;

^**p < 0.01;

^***p < 0.001.

HL, hypothalamic lesion; BMI SDS, body mass index standard deviation scores; OSC, oxytocin saliva concentration; BDI, Beck Depression Inventory; STAI, State-Trait-Anxiety Inventory.

^aincluding patients with and without postoperative HL.