Table 3.

Experimental task results and demographic and clinical variables for patients with postoperative hypothalamic lesions (HL) and controls participating in the Evaluation of Trustworthiness.

Evaluation of Trustworthiness
	All patientsa	Patients with postop HL	All controls	All patients vs. all controls (p-value)	Patients with HL vs. all controls (p-value)
Task Performance
n	20	15	32
Correct evaluation rate (across all items)	0.804 (0.15)	0.767 (0.11)	0.829 (0.16)	0.328	0.135
Correct evaluation rate (for difficult items)	0.677 (0.17)	0.667 (0.15)	0.74 (0.21)	0.214	0.093
Demographic and Clinical Variables
n	20	15	32
% Female gender	60	53.3	56.3	1	1
Age at study (years)	20.5 (10) range: 7–38	21 (9) range: 13–38	23.5 (13) range: 8–40	0.770	0.882
Age at diagnosis (years)	10.5 (6.1)	10.9 (6.48)	–	–	–
BMI SDS	3.73 (6.65)	5.51 (6.63)	0.32 (1.53)	<0.001***	<0.001***
% Radiation therapy	45	46.7	–	–	–
n Baseline OSC	17	13	29
Baseline OSC	3.73 (2.72)	3.73 (2.70)	4.52 (7.82)	0.352	0.327
n BDI_II	15	12	29
BDI-II (raw scores)	6 (11)	9 (10)	4 (5)	0.208	0.038*
n STAI	16	13	28
STAI State (raw scores)	36.5 (12)	38 (12)	31 (6)	0.001***	0.001***
STAI Trait (raw scores)	41.5 (17)	47 (12)	35.5 (9)	0.060	0.008**

For the experimental task, the proportion of correct evaluations is depicted and the primary measure is highlighted in bold. Medians and interquartile ranges (in brackets) are shown, unless otherwise specified. With the exception of gender where we used the χ2- test, all analyses were performed with the Mann-Whitney U-test.

^*p < 0.05;

^**p < 0.01;

^***p < 0.001.

HL, hypothalamic lesion; BMI SDS, body mass index standard deviation scores; OSC, oxytocin saliva concentration; BDI, Beck Depression Inventory; STAI, State-Trait-Anxiety Inventory.

^aincluding patients with and without postoperative HL.