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The effect of BD on cell cycle arrest and apoptosis in MCF-7 and MDA-MB-231 cells. (A,B) The number of MCF-7 and MDA-MB-231 cells in different stages of cell cycle after treatment with different concentrations of BD for 72 h. (C,D) Flow cytometry based on Annexin V/PI double staining to assess extent of apoptosis in two breast cancer lines after treatment with BD for 72 h; *p < 0.05 to control group; **p < 0.01 to control group; ***p < 0.001 to control group (0 μM).
