Figure 5.

MiR-23a protect the hearts form I/R induced injury in rats. (A) qPCR was used to detect the expression of miR-23a in myocardium of rats subjected to ischemia/reperfusion and antagomiR treatment. (B, C) TTC staining was used to detect the infarct area of hearts. (D) LDH, (E) MDA, (F) ROS was evaluated by commercial kits. (G) JC-1 staining was performed to detect the mitochondrial membrane potential (MMP) of myocardium. (H) IHC was performed to evaluate the expression of BCL2L11 in the myocardium. Data are expressed as mean ± SD; n=8 *P<0.05.