Skip to main content
. 2020 Jun 15;12(6):2538–2553.

Figure 2.

Figure 2

LINC01619 promoted NSCLC cells growth in vitro and in vivo. A. LINC01619 expression was up-regulated in NSCLC cell lines (A549, SPCA1, H1299, H1975, H1703, SK-MES-1 and H520) than that in lung bronchial epithelial cell line (BEAS-2B). B. LINC01619 expression in SPCA1 and A549 cells was successfully regulated by transfection. C. LINC01619 up-regulation enhanced SPCA1 and A549 cells viability, whereas LINC01619 down-regulation weakened SPCA1 and A549 cells viability. D and E. LINC01619 up-regulation increased SPCA1 and A549 cells cloning ability, but LINC01619 down-regulation decreased SPCA1 and A549 cells cloning ability. F. On the 28th day of subcutaneous injection, tumor tissues of nude mice in each group were obtained and photographed. G and H. LINC01619 up-regulation promoted NSCLC cells growth in vivo, whereas LINC01619 down-regulation inhibited NSCLC cells growth in vivo. **P < 0.01.