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. 2020 Jun 15;12(6):2538–2553.

Figure 3.

Figure 3

LINC01619 promoted characteristics of tumor stem cells in NSCLC. A and B. LINC01619 up-regulation elevated percentage of ALDH+ cells, while LINC01619 down-regulation reduced percentage of ALDH+ cells. C and D. LINC01619 up-regulation increased the sphere number of ALDH+ cells, but LINC01619 down-regulation decreased the sphere number of ALDH+ cells. E and G. LINC01619 up-regulation enhanced the expression of cancer stem cell markers (ALDH, SOX2, NANOG, OCT4, CD133 and CD44) in SPCA1 and A549 cells. F and H. LINC01619 down-regulation declined the expression of cancer stem cell markers (ALDH, SOX2, NANOG, OCT4, CD133 and CD44) in SPCA1 and A549 cells. *P < 0.05 and **P < 0.01.