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. 2020 Jun 15;12(6):2984–2997.

Table 4.

Prognostic factors for DFS and OS in patients with HBV-related HCC by multivariate COX regression analyses

Variables DFS OS


HR (95% CI) P HR (95% CI) P
Tumor diameter 1.599 (1.180-2.167) 0.002
Tumor number 1.922 (1.430-2.584) < 0.001
Pathological differentiation 1.705 (1.114-2.608) 0.014
GPR 1.900 (1.402-2.574) < 0.001 2.375 (1.287-4.386) 0.006
Fibrinogen 1.921 (1.280-2.885) 0.002 2.395 (1.248-4.599) 0.009
AFP 2.353 (1.321-4.193) 0.004
HBV-DNA 2.286 (1.254-4.165) 0.007

AFP: alpha fetoprotein, HBV: hepatitis B virus, GPR: gamma-glutamyl transpeptidase to platelet ratio, DFS: disease-free survival, OS: overall survival, HR: hazard ratio, CI: confidence interval.