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. 2020 Jun 19;55(2):174–183. doi: 10.14744/TurkPediatriArs.2020.46656

Table 3.

Assessment of high-resolution computed tomography of the lung and pulmonary function test findings in the subjects with humoral immunodeficiency by diagnosis groups

CVID Hyper IgM XLA Selective IgA deficiency IgG subgroup deficiency Total






n % n % n % n % n % n %
Lung HRCT
 Ground-glass opacity 7 30.4 2 40 0 0 0 0 0 0 9 16.6
 Atelectasis 11 47.8 2 40 1 33.3 0 0 1 5 15 27.7
 Bronchiectasis 11 47.8 3 60 1 33.3 0 0 0 0 15 27.7
 Consolidation 2 8.6 2 40 0 0 0 0 0 0 4 7.4
 Bronchial wall thickness 3 13 0 0 0 0 0 0 0 0 3 5.5
 Parenchymal nodule 3 13 2 40 0 0 0 0 0 0 5 9.2
 Pleural effusion 1 4.3 0 0 0 0 0 0 0 0 1 1.8
 Tree in bud 4 17.3 0 0 0 0 0 0 0 0 4 7.4
 Fibrosis 1 4.3 1 20 0 0 0 0 0 0 2 3.7
 Emphysema 0 0 0 0 1 33.3 0 0 0 0 1 1.8
 Hilar LAP 6 26 2 40 0 0 1 25 2 10 11 20.3
 Mediastinal LAP 5 21.7 0 0 0 0 0 0 1 5 6 11.1
 Total 23 100 5 100 3 100 4 100 19 100 54 100
Pulmonary function tests
 Normal 7 31.8 2 40 1 33.3 3 100 15 100 28 58.3
 Mild obstructive 2 9.0 0 0 0 0 0 0 0 0 2 4.1
 Moderate obstructive 2 9.0 0 0 0 0 0 0 0 0 3 6.2
 Marked obstructive 2 9.0 0 0 0 0 0 0 0 0 3 6.2
 Mild restrictive 3 13.6 0 0 0 0 0 0 0 0 3 6.2
 Moderate restrictive 2 5.3 1 20 0 0 0 0 0 0 2 4.1
 Mild obstructive+restrictive 0 0 0 0 0 0 0 0 0 0 1 2.0
 Moderate obstructive +restrictive 4 18 2 40 1 33.3 0 0 0 0 6 12.5
 Total (Number of subjects who underwent pulmonary function test) 22 100 5 100 3 100 3 100 15 100 48 100

Hyper IgM: Hyperimmunoglobulin M syndrome; HRCT: High-resolution computed tomography; CVID: Common variable immunodeficiency; XLA: X-linked agammaglobulinemia; LAP: Lymphadenopathy