Table 3.
Assessment of high-resolution computed tomography of the lung and pulmonary function test findings in the subjects with humoral immunodeficiency by diagnosis groups
CVID | Hyper IgM | XLA | Selective IgA deficiency | IgG subgroup deficiency | Total | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
n | % | n | % | n | % | n | % | n | % | n | % | |
Lung HRCT | ||||||||||||
Ground-glass opacity | 7 | 30.4 | 2 | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 9 | 16.6 |
Atelectasis | 11 | 47.8 | 2 | 40 | 1 | 33.3 | 0 | 0 | 1 | 5 | 15 | 27.7 |
Bronchiectasis | 11 | 47.8 | 3 | 60 | 1 | 33.3 | 0 | 0 | 0 | 0 | 15 | 27.7 |
Consolidation | 2 | 8.6 | 2 | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 7.4 |
Bronchial wall thickness | 3 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 5.5 |
Parenchymal nodule | 3 | 13 | 2 | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 9.2 |
Pleural effusion | 1 | 4.3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1.8 |
Tree in bud | 4 | 17.3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 7.4 |
Fibrosis | 1 | 4.3 | 1 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.7 |
Emphysema | 0 | 0 | 0 | 0 | 1 | 33.3 | 0 | 0 | 0 | 0 | 1 | 1.8 |
Hilar LAP | 6 | 26 | 2 | 40 | 0 | 0 | 1 | 25 | 2 | 10 | 11 | 20.3 |
Mediastinal LAP | 5 | 21.7 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 6 | 11.1 |
Total | 23 | 100 | 5 | 100 | 3 | 100 | 4 | 100 | 19 | 100 | 54 | 100 |
Pulmonary function tests | ||||||||||||
Normal | 7 | 31.8 | 2 | 40 | 1 | 33.3 | 3 | 100 | 15 | 100 | 28 | 58.3 |
Mild obstructive | 2 | 9.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.1 |
Moderate obstructive | 2 | 9.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 6.2 |
Marked obstructive | 2 | 9.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 6.2 |
Mild restrictive | 3 | 13.6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 6.2 |
Moderate restrictive | 2 | 5.3 | 1 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.1 |
Mild obstructive+restrictive | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.0 |
Moderate obstructive +restrictive | 4 | 18 | 2 | 40 | 1 | 33.3 | 0 | 0 | 0 | 0 | 6 | 12.5 |
Total (Number of subjects who underwent pulmonary function test) | 22 | 100 | 5 | 100 | 3 | 100 | 3 | 100 | 15 | 100 | 48 | 100 |
Hyper IgM: Hyperimmunoglobulin M syndrome; HRCT: High-resolution computed tomography; CVID: Common variable immunodeficiency; XLA: X-linked agammaglobulinemia; LAP: Lymphadenopathy