TABLE 3.
Clinical data of PD patients and healthy controls included in the tandem mass tag-based proteomics analysis.
| Variable (SEM/%) | HC (27) | PD (30) | p-value | Variable (SEM/%) | HC (27) | PD (30) | p-value |
| Age (year) | 66.59 ± 1.14 | 69.17 ± 1.50 | 0.184 | HbA1c (%) | 5.99 ± 0.18 | 6.17 ± 0.19 | 0.515 |
| Gender, Male (%) | 14 (51.9%) | 19 (63.3%) | 0.381 | TC (mmol/L) | 4.33 ± 0.17 | 4.32 ± 0.16 | 0.952 |
| Smoking history (%) | 9 (33.3%) | 7 (23.3%) | 0.402 | TG (mmol/L) | 1.49 ± 0.15 | 1.23 ± 0.14 | 0.206 |
| Alcohol consumption (%) | 3 (11.1%) | 1 (3.3%) | 0.53 | HDL-C (mmol/L) | 1.21 ± 0.08 | 1.24 ± 0.09 | 0.858 |
| Hypertension (%) | 15 (55.6%) | 13 (43.3%) | 0.357 | LDL-C (mmol/L) | 2.81 ± 0.15 | 2.73 ± 0.13 | 0.679 |
| Diabetes mellitus (%) | 2 (7.4%) | 5 (16.7%) | 0.51 | Apo-A1 (g/L) | 1.31 ± 0.05 | 1.30 ± 0.05 | 0.93 |
| Hypercholesterolemia (%) | 4 (14.8%) | 6 (20.0%) | 0.869 | Apo-B (g/L) | 0.89 ± 0.04 | 0.85 ± 0.04 | 0.403 |
| BMI (kg/m2) | 23.95 ± 0.69 | 22.79 ± 0.58 | 0.197 | Lpa (mg/L) | 201.19 ± 48.58 | 270.04 ± 66.49 | 0.407 |
| UPDRS score | / | 38.49 ± 3.98 | / | Hoehn-Yahr score | / | 2.40 ± 0.16 | / |
PD, Parkinson’s disease; SEM, standard error of the mean; HC, healthy control; HbA1c, hemoglobin A1c; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Apo-A1, apolipoprotein A1; Apo-B, apolipoprotein B; BMI, body mass index; Lpa, lipoprotein a; UPDRS, Unified Parkinson’s Disease Rating Scale.