Figure 1.

Annual production of the schedule II regulated ADHD drugs amphetamine (red) and methylphenidate (blue, left scale, x 1,000 kg) and adult patients annually receiving antidepressant drugs in the United States (yellow, right scale, x 1,000,000). The production of the ADHD drugs has increased more than thirtyfold, the number of MDD patients receiving antidepressants about threefold in the shown period. It must be also noted, though, that in the period shown the criteria for diagnosing ADHD changed, for example, with respect to adult ADHD and the DSM-5 of 2013 (20). Source: updated from (28), US Federal Register; (29).