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. 2020 Jun 25;9(6):358. doi: 10.3390/antibiotics9060358

Table 2.

Minimum inhibitory and bactericidal concentration (MIC/MBC) [mg/mL] of cajeput, lemongrass, tea tree, and thyme essential oils against 27 uropathogenic strains in artificial urine, determined by broth microdilution assay. Median values from three independent measurements are shown.

Bacterial Strain 1 Antibiotic Resistance Essential Oils
Cajeput Lemongrass Tea Tree Thyme
MIC MBC MIC MBC MIC MBC MIC MBC
Ec ATCC 25922 12.5 12.5 25 25 1.56 1.56 1.56 1.56
Ec CHD1 3.13 3.13 1.56 3.13 1.56 1.56 0.78 1.56
Ec CHD3 3.13 3.13 0.63 6.25 1.56 1.56 0.78 0.78
Ec CHD22 3.13 3.13 25 25 1.56 1.56 1.56 1.56
Ec CHD94 6.25 6.25 25 25 1.56 1.56 1.56 1.56
Ec UTI89 6.25 6.25 25 25 1.56 1.56 0.78 0.78
Ec CHD16 bla CTX-M-15 6.25 12.5 12.5 25 3.13 6.25 3.13 3.13
Ec IR3 blaCTX-M-15, blaTEM-1B 3.13 6.25 1.56 1.56 3.13 3.13 1.56 3.13
Ec H75 bla NDM-1 12.5 12.5 25 25 3.13 3.13 3.13 6.25
Ec 1949820 fluoroquinolone 25 50 50 50 3.13 0.78 3.13 3.13
Ec CDF2 mcr-1 1.56 1.56 1.56 1.56 1.56 1.17 0.78 0.78
Kp 595 3.13 3.13 3.13 3.13 1.56 1.56 1.56 1.56
Kp CHD67 3.13 3.13 3.13 6.25 1.56 1.56 1.56 1.56
Kp CHD99 25 50 50 50 3.13 3.13 25 50
Kp ATCC BAA1705 bla KPC 25 50 25 25 3.13 3.13 6.25 12.5
Kp ATCC BAA2146 bla NDM-1 12.5 50 25 50 6.25 6.25 25 50
Ecl CHD57 25 50 25 25 1.56 3.13 1.56 1.56
Ecl CHD60 3.13 6.25 6.25 12.5 0.78 1.56 0.78 0.78
Pm CHD72 25 50 25 25 6.25 6.25 25 25
Pm CHD76 50 50 12.5 25 6.25 6.25 25 25
Pa ATCC 27853 50 50 25 50 12.5 50 25 50
Pa CHD80 25 50 25 50 25 25 25 50
Pa CHD81 50 50 25 50 50 50 50 50
Ef CHD30 6.25 6.25 3.13 1.56 12.5 12.5 6.25 6.25
Ef CHD31 12.5 12.5 1.56 1.56 12.5 12.5 6.25 12.5
Ss Ho94 1.56 1.56 0.78 0.78 1.56 1.56 1.56 1.56

1 Ec—Escherichia coli, Kp—Klebsiella pneumoniae, Ecl—Enterobacter cloacae, Pm—Proteus mirabilis, Pa—Pseudomonas aeruginosa, Ef—Enterococcus faecalis, Ss—Staphylococcus saprophyticus.