Table 2.

Pathotypes of E. coli strains [20,21,22].

Intestinal/Diarrheagenic E. coli	Extraintestinal E. coli
MAJOR PATHOGENIC CATEGORIES
InPEC Pathotypes: enteropathogenic E. coli (EPEC) enterohemorrhagic E. coli (EHEC) Shigatoxin producing (STEC) enterotoxigenic E. coli (ETEC) enteroinvasive E. coli (EIEC) enteroaggregative E. coli (EAEC) diffusely adherent E. coli (DAEC)	ExPEC Pathotypes: uropathogenic E. coli (UPEC) neonatal meningitis E. coli (NMEC)
Factors Inducing Pathogenicity: immune disorder, immunodeficiency crossing gastrointestinal barriers (e.g., peritonitis) evolutionary modification of the bacterial genome