Table 2.
Platelet-rich plasma (PRP) compared with control intervention for the knee adjacent muscle injuries.
| LOE | Type of Study | Exp. | Cont. | Follow-up | Control | Preparation Kit | LR/LP | Platelet Concentration | Number of Injections | PROM | Ref. | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hamid et al. | II | 2 arms | 14(12) | 14(12) | 39 weeks | No injection | GPS III (Biomet) | 38.3 × 103/µL | 1297 × 103µL | 1 | RTS BPI-SF |
[11] |
| Hamilton et al. | I | 3 arms | PRP 30(26) PPP 30(28) |
30(29) | 6 months | No injection | GPS III (Biomet) | 26.1(13.7) × 103/µL | 765.8(23.6) × 109/L | 1 | RTS Re-injury |
[12] |
| Reurink et al. | I | 2 arms | 41(37) | 39(36) | 1 year | Saline | ACP (Athrex) | 1.9(2.1) × 103/µL | 433(128) × 103/µL | 2 | RTS Re-injury |
[13] |
| Rossi et al. | I | 2 arms | 35(34) | 40(38) | 2 years | No injection | N/R | N/R | N/R | 1 | RTS VAS Re-injury |
[10] |
LOE—level of evidence; exp.—no. of patients receiving treatment in experimental group (no. of patients analyzed at final follow-up); cont.—no. of patients receiving treatment in control group (no. of patients analyzed at final follow-up); LR—leukocyte rich; LP—leukocyte poor; PROM—patient related outcome measures; VAS—visual analog scale; RTS—time for return to sports; BPI-SF—Brief Pain Inventory-Short Form.