Table 3.
Platelet-rich plasma (PRP) compared with control intervention for high tibial osteotomy.
LOE | Type of Study | Exp. | Cont. | Follow-up | Control | Preparation Kit | LR/LP | Platelet Concentration | Number of Injections | PROM | Ref. | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Dallari et al. | I | 3 arms | PG 1(9) PG + BM 12(10) |
10(9) | 1 year | Lyophilized bone chips |
N/R | N/R | 1 × 106/µL | 1 | KSS ROM Osteointegration histomorphometric |
[15] |
Koh et al. | II | 2 arms | 26(23) | PRP + MSC 26(21) | 2 years | PRP + MSC | N/R | N/R | 1303.27 (375.2) × 103/µL | 1 | Lysholm VAS KOOS |
[14] |
LOE—level of evidence; exp.—no. of patients receiving treatment in experimental group (no. of patients analyzed at final follow-up); cont.—no. of patients receiving treatment in control group (no. of patients analyzed at final follow-up); LR—leukocyte rich; LP—leukocyte poor; ROM—range of movement; PROM—patient related outcome measures; VAS—visual analog scale; KSS—Knee Society Score; Lysholm—Lysholm Knee Scoring Scale.