Figure 3.

Effect of the topically applied COEFC–C. rhamnifolioides essential oil complexed in β-Cyclodextrin (0.83, 4.17, and 8.35 mg/mL) on ear edema induced by a single croton oil application in mice. Results of the mean value of the edema percentage between the control (C), dexamethasone (D) (4 mg/mL), and COEFC (0.83, 4.17, and 8.35 mg/mL) groups. Values represent the mean ±E.P.M. (standard error of the mean) for groups of 6 animals. Being, ** p < 0.01; vs. control; Statistical analysis: ANOVA followed by the Dunnett’s test with multiple comparisons.