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. 2020 May 30;9(6):114. doi: 10.3390/biology9060114

Table 2.

Binding energy of the interaction the different ligands with prostaglandin G/H synthase 2 by the autodock procedure (cyclooxigenase 2).

Ligand Energy (kcal/mol) Est. Inhibition Constant, Ki* (µM or ηM)
Prostaglandin E2 (Natural ligand) −4.8 433.11 µM
Celecoxib −10.4 70.80 ηM
Diclofenac −8.4 13.2 µM
Meloxicam −9.1 3.02 µM
Naproxen −8.4 14.26 µM
1,8-Cineole −6.0 31.12 µM

* Theorical Inhibition Constant calculated by autodock function. Ki unit is µM = micromoles or ηM = nanomols.