Table 1.
Demographics and Baseline Data.
| Pre-Intervention (n = 81) |
Post-Intervention (n = 79) |
p Value | |
|---|---|---|---|
| Age, years, mean ± SD | 50.6 ± 20.1 | 49.9 ± 17.5 | 0.8 |
| Female sex, n (%) | 35 (43.2) | 49 (62) | 0.02 |
| Race | − | − | 0.10 |
| White, n (%) | 60 (74.1) | 63 (79.7) | − |
| African American, n (%) | 18 (22.2) | 9 (11.4) | − |
| Other/unknown, n (%) | 3 (3.7) | 7 (8.9) | − |
| ICU admission, n (%) | 26 (32.1) | 19 (24.1) | 0.26 |
| 30-day mortality, n (%) | 5 (6.2) | 3 (3.8) | 0.72 |
| Peripheral WBC, k/µL, mean ± SD | 9.6 ± 4.2 | 10.5 ± 6.1 | 0.29 |
| CSF WBC, per µL, mean ± SD | 61 ± 157 | 162 ± 798 | 0.27 |
| CSF neutrophils, %, mean ± SD | 21 ± 31 | 18 ± 29 | 0.51 |
| CSF lymphocytes, %, mean ± SD | 58 ± 33 | 58 ± 34 | 0.94 |
| CSF glucose, mg/dL, mean ± SD | 80 ± 38 | 76 ± 26 | 0.37 |
| CSF protein, mg/dL, mean ± SD | 57 ± 34 | 60 ± 46 | 0.56 |
| Traumatic LP, n (%) | 8 (9.9) | 6 (7.6) | 0.61 |
| Antimicrobial pretreatment prior to LP, n (%) | 36 (44.4) | 33 (41.8) | 0.73 |
Abbreviations: SD: Standard deviation, ICU: Intensive care unit, WBC: White blood cell count, CSF: Cerebrospinal fluid, LP: Lumbar puncture.