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Effects of KAN0441571C (250 nM) (4 h) on ROR1 associated signaling molecules (Western blot) in the DLBCL cell line OCI-Ly3. ROR1, LRP6, SRC, PI3Kδ, PKC, AKT, mTOR, and CREB were dephosphorylated, CK1δ was downregulated and β-catenin was destabilized. Data are representative of three individual experiments.
