Table 2.
Endophytic fungi applied for biotransformation.
| Patent No. | Endophyte | Host 1 | Patent Details | Ref. |
|---|---|---|---|---|
| CN102080048A | Absidia glauca | gingsen | Conversion of ginsenoside Rb1 (230) to prepare ginsenoside Rd (231). | [245] |
| CN102080049A | Zygorhynchus moelleri | Panax gingsen | Preparation of ginsenoside Rd from ginsenoside Rb1. | [246] |
| CN102154123A | Fusarium sp. | Dioscorea nipponica | Biotransformation conversion conditions of diosgenin saponins. | [247] |
| CN102199548A | Penicillium oxalicum | Polygonun cuspidatum | Microbial transformation of resveratrol from polydatin (232). | [248] |
| CN102212486A | Penicillium oxalicum | Polygonun cuspidatum | Conversion of polydatin into resveratrol. | [249] |
| CN102392050A | Penicillium sp. | Not disclosed | Biotransformation of raisin extract. Preparation and application in flavoring. | [250] |
| CN102757443A | Several endophytes featuring Penicillium purpurogenum | Dysosma sp. or Sabina vulgaris | Separation and purification method for bioconversion of podophyllotoxin into sulfur-substituted derivatives. | [251] |
| CN103695478A | fungal strain L1 CGMCC No. 4558 | Not disclosed | Conversion of polydatin to resveratrol. | [252] |
| CN103981104A | Microsphaeropsis arundinis | wild rice | Biotransformation of glycyrrhizinic acid (233) into liquiritin (234). | [253] |
| CN103992953A | Aspergillus flavus | wild rice | Transform glycyrrhizic acid into glycyrrhetinic acid monoglucuronide (235). | [254] |
| CN106591142A | Xylariales sp. | Not disclosed | Conversion of Panax notoginseng saponin to prepare vina-ginsenoside R13 (236), notoginsenoside J (237) and American saponin ginseng L16 (238). | [255] |
| CN106701604A | Chaetomium globosum | wild rice | Conversion of glycyrrhizic acid into glycyrrhetinic acid monoglucuronide. | [256] |
| CN106893677A | Fusarium sp. | Herba Andrographitis | Transformation of andrographolide diterpenoids (239–242). | [257] |
| CN107034253A | Fusarium oxysporum | Gentiana sp. | Conversion of gentiopicroside (243) into two separate compounds with hepatoprotective activity. | [258] |
| CN107312720A | Fusarium proliferatum | Cajanus cajan | Conversion of ginsenoside Rb1 into ginsenoside Rd and its application. | [259] |
| CN108707553A | Plectosphaerella cucumerina | Huperzia serrata | Efficient conversion of androstenedione to testolactone and androstane diene diketone. | [260] |
| CN109536561A | Fusarium oxysporum | gingsen | Conversion of ginsenoside Rb1 into the rare ginsenoside CK (244). | [261] |
| CN110527632A | Phomopsis sp. | Not disclosed | Bioconversion of betulinic acid (245). | [262] |
| CN110423697A | Lasiodiplodia pseudotheobromae | Illicium verum | trans-trans-Anethole (246) conversion to generate different vanillic acids (247). | [263] |
| US20190264295A1 | Ovatospora brasiliensis | Curcuma sp. | Microbial bioconversion of curcuminoids to calebin A (248). | [264] |
| WO2019070219A2 | Alternaria eureka/Neosartorya hiratsukae/Camarosporium laburnicola | Astragalus condensatus, A. angustifolius | Production of a telomerase activator, biotransformation with endophytic fungi to obtain new/novel molecules from the saponins from natural sources and method for discovery molecules that increase telomerase enzyme activation. | [265] |
1 Some patents just provided a common name for the host organism.