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The effect of javamide-II on the phosphorylation of p38. The samples were prepared using PMA-differentiated THP-1 cells treated with javamide-II (0, 10, 20, 40 µM) followed by treatment with LPS for 45 min. Data points represent the means ± SD (n = 5). The P value was calculated using one-way ANOVA with the Holm–Sidak method, and the asterisks (*) indicate significant differences (P < 0.05) compared to the p38 control.
