Table 2.
Brain FDG-PET analysis.
| Case | Antibodies Type | Visual Assessment | SPM | Syngo.via Database Comparison | Neurostat 3D-SSP | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| p < 0.001 | p < 0.005 | ||||||||||
| Hypo | Hyper | Hypo | Hyper | Hypo | Hyper | Hypo | Hyper | Hypo | Hyper | ||
| 1 | NMDAR | L Frontal, L&R Temporal, Occipital, Motor cortex | L lateral Temporal | R MTL and lateral Temporal, L Frontal. R Motor cortex | R. Insula; L lateral Temporal, L&R Parietal; PC | Similar locations but more extended | Similar locations but more extended | L&R Frontal, R temporal, occipital, L&R Motor cortex | L temporal, medial Frontal, Insula, PC, L&R Parietal, Cerebellum | L&R Frontal, R temporal, occipital, L&R Motor cortex | L Temporal, medial Frontal, Insula, PC, L&R Parietal, Cerebellum |
| 2 | LGI-1 | Frontal, Parietal, Temporal, Thalamus, Occipital. | L&R BC | Orbitofrontal, L Temporal | L&R BG, Cerebellar vermis; L&R MTL | Similar locations and R Parietal | Similar locations but more extended | L&R Lateral Frontal, L Temporal, L&R Parietal, R PC | L&R BG, Cerebellar vermis, L&R MTL | L&R Lateral Frontal, lateral Temporal, Parietal, PC | L&R BG, Cerebellar vermis, L&R MTL |
| 3 | CASPR2 | - | R. MTL R. BG |
- | R MTL, R BG | L&R Frontal, R. Temporal | L&R MTL; R BG; Occipital | Frontal, R Temporo-Parietal | L&R MTL, R BG, Occipital | R. Frontal | L&R MTL |
| 4 | LGI-1 | L Frontal, L&R parietal | L&R MTL, Cerebellar vermis, R BG | L&R Frontal, L&R lateral Temporal, R Parietal, L PC | L MTL | Similar but more extended, L&R Parietal, L&R PC | L&R MTL | L&R Frontal, L&R Parietal, L&R PC | L&R MTL Cerebellar Vermis, L&R BG, L&R Motor cortex | L&R Frontal, R Parietal, L&R PC | L&R MTL, Cerebellar vermis, Motor cortex, L&R |
| 5 | Negative | L Frontal, L lateral Temporal | PreCuneus, Occipital | L&R Frontal, L&R Temporal | - | L&R Frontal, R Insula, L&R Temporal | R Parietal | L&R Frontal, L&R Parietal, L Temporal | Parieto-Occipital, Precuneus, | L&R Frontal | Parieto-Occipital |
| 6 | CASPR2 | - | L.MTL. | L&R Fronto-temporal | - | Similar locations but more extended, Parietal | - | L&R Fronto-temporal | L MTL. | L&R Fronto-temporal | L MTL, Parieto-Occipital |
Hyper: Hypermetabolism; Hypo: Hypometabolism; L: Left; R: Right; PC: Posterior cingulate; BC: Basal ganglia; MTL: Medial temporal lobe.