Table 3.
Description of CITCj625-18 (representative of CITCj727-18) multidrug resistance genomic island.
| Locus Tag | Gene Annotation |
InterProScan Protein Family or Domain | GenBank Accession Number of Closest (% Identity/% Coverage) | Predicted Function |
|---|---|---|---|---|
| HBF06_00624 | Holliday junction ATP-dependent DNA helicase, RuvB | IPR004605 |
WP_002856258.1 100/100 |
Holliday junction helicase (strand exchange reactions in homologous recombination) |
| HBF06_00625 | Histidine phosphotransferase | IPR036641 | MPA99107.1 100/90) |
Signal transduction |
| HBF06_00627 | Autotransporter adhesion, CapC | IPR005546 | EAK6247206.1 99.16/94 | Protein secretion |
| HBF06_00628 | Truncated tetracycline resistance ribosomal protection protein, TetO | IPR035650 |
AUA17601.1 99.59/82 |
Ribosomal protection protein conferring tetracycline resistance (TetO) |
| HBF06_00629 | Aminoglycoside 6- nucleotidyltransferase, ANT(6)-Ib |
IPR007530 |
WP_001255868.1 100/100 |
Adenylyltransferase activity conferring resistance to aminoglycosides |
| HBF06_00630 | Replication protein, RepB | IPR002631 |
WP_052777339.1 100/100 |
Plasmid replication protein |
| HBF06_00631 | DNA topoisomerase | IPR000380 |
WP_139898553.1 99.52/100 |
Topoisomerisation and single stranded breakage during transcription, DNA replication and recombination. |
| HBF06_00632 | Streptothricin acetyltransferase, SatA | IPR008125 |
EOO12820.1 96.86/100 |
Acetylation of streptothricin conferring resistance |
| HBF06_00633 | Mosaic tetracycline resistance ribosomal protection protein, TetO/32/O | IPR035650 |
WP_052855148.1 100/100 |
Ribosomal protection protein conferring tetracycline resistance |
| HBF06_00634 | Plasmid replication protein | None detected | EDP4862066.1 99.21/97 |
Plasmid replication |