Table 1.
Experiments with anti-IDs mimicking bioregulators.
| Anti-ID Bearing Internal Image of … | Biological Effects of Anti-ID | Authors |
|---|---|---|
| Human interferon-γ (IFN-γ) | Binding to the receptor of HuIFN-γ and reproduces antiviral activity | Depraetere et al. [21] |
| Interleukin-1 (IL-1) | Enhancing proliferation of thymocytes | Zuberi et al. [22] |
| Angiotensin | Binding to angiotensin receptors | Couraud et al. [23] |
| Basophil-bound idiotype | Altering histamine release from basophils | Mecheri et al. [26] |
| Haloperidol | Binding to D-2 dopamine receptors | Elazar et al. [27] |
| Dopamine | Inhibiting binding of dopamine to rat brain membranes | Mons et al. [28] |
| Acethylcholine-receptors | Similar binding abilities for cholinergic ligands | Eng et al. [29] |
| Serotonin (5-hydroxytryptamine, 5-HT) | Recognizing 5-HT1B, 5-HT1C and 5-HT2 receptor subtypes | Tamir et al. [30] |
| β2-adrenergic receptor | Agonistic activity | Werner et al. [32] Junemann et al. [33] |
| β1-adrenergic receptor | Agonistic activity | Bornholz et al. [34] |
| α1-adrenergic receptor | Agonistic activity | Karczewski et al. [35] |
| Insulin | Binding to insulin receptors on thymocytes | Sege et al. [37] Elias et al. [41] Taylor et al. [42] Chong et al. [43] |
| Estradiol | Recognizing of estrogen receptor | Mor et al. [38] |
| Growth hormone | Binding to growth hormone receptors, stimulation of porcine hepatocytes to secrete insulin-like growth factor-1 | Lan et al. [39] |
| Prolactin | Prolactin-like activity on casein gene expression and DNA synthesis | Djiane et al. [49] Dusanter-Fourt et al. [51] |
| Thyrotropin | Inhibition biding of thyroid stimulating hormone to thyroid plasma membranes and stimulating their adenylate cyclase activity | Farid et al. [58,59,60,61] |
| ACTH | Stimulation of isolated adrenal cells to secrete corticosterone, inhibition of mitotic activity in adrenal cells. | Clarke et al. [78] |
| HEC toxin of Aeromonas hydrophila | Induction of specific immune reactivity to natural microbial antigen | Chen et al. [62] |
| Mycotoxin of dothistromin | Binding to dothistromin-protein conjugates | Jones et al. [63] |
| Killer toxin (KT) of Pichia anomala | Reaction with KT receptors, therapeutic activity in experimental rat model of vaginal thrush | Magliani et al. [64] |
| Phleum pretense grass pollen allergen | Therapeutic effect on experimental mice model of acute allergic asthma | Hantusch et al. [65] |
| Alprenalol | Binding to β-adrenergic receptors, stimulating of basal adenylate cyclase activity, modulation of catecholamine signal transmission | Schreiber et al. [67] |
| Naloxone | Binding to opiate receptors | Ng et al. [69] |
| Morphine | Inhibition of the morphine binding to opiate receptors | Glasel et al. [70] |
| β-endorphin | Opiate antagonistic activity | Gramsch et al. [71] Roy et al. [72] |
| Cocaine | Binding to hDAT | Ho et al. [74] |