Table 3.
Median times for the main outcomes.
| Time-to-Outcome Intervals | Total Sample | Stratified for Sex | Stratified for Age | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Males | Females | Age <55 Years | Age ≥55 Years | |||||||
| n at Day 0 | Outcomes | Censored | Median (IQR) | Median (IQR) | Median (IQR) | p-Value 1 | Median (IQR) | Median (IQR) | p-Value 1 | |
| Date of perceived risk contact to Start of symptoms 2 | 39 | 39 | 0 | 4 (3, 7) | 5 (3, 7) | 4 (2, 7) | 0.387 | 5 (3, 7) | 4 (2, 5) | 0.125 |
| Start of symptoms to End of symptoms | 76 | 55 | 21 | 14 (10, -) | 13 (8, 17) | 17 (11, -) | 0.024 | 14 (10, 22) | 19 (11, -) | 0.129 |
| Start of symptoms to First positive PCR 3 | 76 | 76 | 0 | 2 (1, 5) | 2 (1, 4) | 3 (1, 5) | 0.081 | 2 (1, 4) | 3 (1, 6) | 0.784 |
| Start of symptoms to Negative PCR | 76 | 44 | 32 | 31 (21, -) | 21 (18, -) | 33 (25, -) | 0.025 | 28 (10, 39) | 33 (25, -) | 0.207 |
| First positive PCR to Negative PCR | 76 | 44 | 32 | 25 (18, 37) | 19 (16, -) | 30 (22, 37) | 0.076 | 22 (17, 37) | 31 (23, -) | 0.119 |
| End of symptoms to Negative PCR 4 | 53 | 33 | 20 | 15 (9, 25) | 10 (8, 16) | 17 (12, 24) | 0.322 | 13 (8, 24) | 18 (14, 26) | 0.522 |
The upper limit (p75%) of the IQR could not be obtained in some groups due to censoring. 1 p-values assess differences in the hazard ratio of each outcome across age and sex groups, obtained from the corresponding Cox regression model including age and sex as covariates. 2 For this outcome, 37 patients could not recall any risk contact. 3 We assigned a value of 0.5 days in 10 patients who reported that symptom onset and their first positive PCR result occurred on the same day. 4 Of 55 patients with a date for end of symptoms (not censored for this outcome), one had a negative PCR result 4 days before the date of end of symptoms, and another had a negative PCR result the same date as the end of symptoms; both patients were excluded from this analysis.