Table 1.

Diagnostic criteria for severe asthma with fungal sensitization (SAFS) in adults and children.

Fungal Sensitization (Positive Skin Prick Test and/or Specific IgE to One or More Fungus)	Other Adult Criteria	Other Paediatric Criteria
Aspergillus fumigatus Cladosporium herbarum Penicillium chrysogenum (notatum) Candida albicansa Trichophyton mentagrophytes Alternaria alternate Botrytis cinere	Treatment with 500 mcg Fluticasone Propionate/day, or Continuous oral corticosteroids, or 4 prednisolone bursts in 12 months or 6 bursts in 24 months	Severe, therapy resistant asthma (ERS/ATS Task Force criteria)
	IgE < 1000	IgE can be any level
	Negative IgG precipitins to Aspergillus fumigatus	IgG precipitins to Aspergillus fumigatus can be positive or negative