Table 2.

Unanswered questions in the field of fungal asthma.

No.	Unanswered Questions
1	Is the concept of fungal asthma, comprising SAFS and low-grade fungal bronchitis, a useful one?
2	Are fungal allergens qualitatively different in their effects from other aeroallergens, or is fungal sensitization merely a manifestation of poly-sensitization?
3	Is the significance of fungal asthma different in children with severe asthma, when multiple aeroallergen sensitization is much more common, compared with adults?
4	There are multiple fungi which could be significant, and molecular techniques will detect fungi with ever greater sensitivity, so we what biomarkers will enable us to differentiate fungi causing pathology from those which are harmless commensals?
5	Are there different fungal asthma, with different molecular pathways; in other words, are all fungi equal and equivalent, which seems unlikely?
6	How do fungi interact with other aeroallergens, viruses and bacteria within the airway?
7	Should anti-neutrophilic strategies such as azithromycin be used to mitigate the effects of neutrophilic inflammation and tissue damage?