Table 3.

List of different hydrophilic and hydrophobic amino acids with corresponding logP values. The lipophilicity of these amino acids, expressed as their logP, ranges from −4.3 to −1.38, where asparagine with logP value of −4.3 being the least lipophilic and phenylalanine with a logP of −1.38 being the most lipophilic or hydrophobic amino acid. It also shows that hydrophilic amino acids are either charged, uncharged or polar molecules, while hydrophobic amino acids are mostly uncharged and nonpolar.

Hydrophilic Amino Acids	Charged (+/−/Uncharged)	logP	Hydrophobic Amino Acids	Charged (+/−/Uncharged)	logP
Asparagine	Uncharged	−4.3	Arginine	+	−4.2
Aspartic acid	−	−3.89	Cysteine	Uncharged	−2.49
Glutamine	Uncharged	−3.64	Isoleucine	Uncharged	−1.7
Glutamic acid	−	−3.69	Glycine	Uncharged	−3.4
Histidine	+	−3.32	Phenylalanine	Uncharged	−1.38
Lysine	+	−3.05	Serine	Uncharged	−3.07
Threonine	Uncharged	−3.5	Leucine	Uncharged	−1.6
Tyrosine	Uncharged	−2.4	Valine	Uncharged	−2.26