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. 2020 May 11;9(2):14. doi: 10.3390/antib9020014

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Native LL37 and cit-LL37 are present in circulation of RA and SLE patients. (a) RA and SLE sera were diluted 1–100 in ELISA plates coated with MRB139 or MRB142 (1:50) and ELISA was performer as in Material and Methods. Horizontal bars are the means; vertical bars are standard errors of the mean, p values calculated by Mann-Whitney test. Sample size indicated in brackets. The horizontal line indicates cut-off determined by reactivity of HD, as explained in Material and Methods. (b) Correlation by Spearman’s correlation test (two-tailed) between presence of native LL37 or cit-LL37 in blood and disease status (expressed as clinical SLEDAI).