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. 2020 Jun 25;10(6):130. doi: 10.3390/membranes10060130

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Transmission electron microscopy of S. aureus treated with antibiotics (Menadione MIC/4) and Antibiotic CIM/4). (A) General view: some cells exhibit abnormal electron density in the cytoplasm (★) and altered cell wall with no visible tripartite-layers structure (black arrowheads). (B) Inset of Figure A. (C) Detailed view of a cell showing alterations in the shape, loss of cytosolic electron-density (★) and mesosome-like structures (M). (D) A lysed cell with cell wall disruption (arrow) and cytoplasmic disintegration (asterisk). Bars: A: 500 nm; B–D: 200 nm.

Transmission electron microscopy of S. aureus treated with antibiotics (Menadione MIC/4) and Antibiotic CIM/4). (A) General view: some cells exhibit abnormal electron density in the cytoplasm (★) and altered cell wall with no visible tripartite-layers structure (black arrowheads). (B) Inset of Figure A. (C) Detailed view of a cell showing alterations in the shape, loss of cytosolic electron-density (★) and mesosome-like structures (M). (D) A lysed cell with cell wall disruption (arrow) and cytoplasmic disintegration (asterisk). Bars: A: 500 nm; B–D: 200 nm.