Table 1.
Species | Peaks Retention Time (min) | Mascot Results Matching the Exact Mass | m/z Values from MS Data | Exact Mass from MS Data | Exact Mass Calculated from Mascot Data | Toxin Class | Varespladib Concentration Required for Full Inhibition |
---|---|---|---|---|---|---|---|
B . asper | 23.2–24.1 | PA2H2_BOTAS | 1373.368810+ | 13,714.5646 | 13,714.56817 | PLA2 | 0.8 μM |
24.3–25.8 | PA2HA_BOTAS | 1266.598511+ | 13,912.4649 | 13,896.51308 | PLA2 | 20 μM | |
24.3–25.8 | PA2H3_BOTAS | 1378.369710+ | 13,765.5812 | 13,765.58896 | PLA2 | 20 μM | |
24.3–25.8 | PA2B3_BOTAS | 1164.881112+ | 13,957.5333 | 13,957.48720 | PLA2 | 20 μM | |
24.3–25.8 | PA2A2_BOTAS | - | - | 14,194 | PLA2 | 20 μM | |
D. russelii | 23.9–27.4 | PA2B8_DABRR | 1511.69629+ | 13,587.2248 | 13,587.2027 | PLA2 | 20 μM |
23.9–27.4 | PA2B5_DABRR | 13,587 | PLA2 | 20 μM | |||
23.9–27.4 | PA2B3_DABRR | - | - | 13,687 | PLA2 | 20 μM | |
E. carinatus | |||||||
23.3–24.4 | PA2A1_ECHCA | - | - | 16,310 | PLA2 | 0.8 μM | |
O. scutellatus | 22.6–25.1 | PA2TA_OXYSC | - | - | 13,829 | PLA2 | 20 μM |
22.6–25.1 | PA2TB_OXYSC | - | - | 16,008 | PLA2 | 20 μM | |
23.6–25.1 | PA21_OXYSC | - | - | 16,898 | PLA2 | 20 μM | |
23.6–25.1 | PA2TC_OXYSC | - | - | 13,313 | PLA2 | 20 μM |