Skip to main content
. 2020 Jun 17;8(6):165. doi: 10.3390/biomedicines8060165

Table 1.

Correlated accurate molecular masses and proteomics data for PLA2 activities (peak retention times are adapted from Figure 3).

Species Peaks Retention Time (min) Mascot Results Matching the Exact Mass m/z Values from MS Data Exact Mass from MS Data Exact Mass Calculated from Mascot Data Toxin Class Varespladib Concentration Required for Full Inhibition
B . asper 23.2–24.1 PA2H2_BOTAS 1373.368810+ 13,714.5646 13,714.56817 PLA2 0.8 μM
24.3–25.8 PA2HA_BOTAS 1266.598511+ 13,912.4649 13,896.51308 PLA2 20 μM
24.3–25.8 PA2H3_BOTAS 1378.369710+ 13,765.5812 13,765.58896 PLA2 20 μM
24.3–25.8 PA2B3_BOTAS 1164.881112+ 13,957.5333 13,957.48720 PLA2 20 μM
24.3–25.8 PA2A2_BOTAS - - 14,194 PLA2 20 μM
D. russelii 23.9–27.4 PA2B8_DABRR 1511.69629+ 13,587.2248 13,587.2027 PLA2 20 μM
23.9–27.4 PA2B5_DABRR 13,587 PLA2 20 μM
23.9–27.4 PA2B3_DABRR - - 13,687 PLA2 20 μM
E. carinatus
23.3–24.4 PA2A1_ECHCA - - 16,310 PLA2 0.8 μM
O. scutellatus 22.6–25.1 PA2TA_OXYSC - - 13,829 PLA2 20 μM
22.6–25.1 PA2TB_OXYSC - - 16,008 PLA2 20 μM
23.6–25.1 PA21_OXYSC - - 16,898 PLA2 20 μM
23.6–25.1 PA2TC_OXYSC - - 13,313 PLA2 20 μM