. 2020 Jun 23;5(26):15805–15811. doi: 10.1021/acsomega.0c00468

Table 1. IC₅₀ Values of the Derivatives in Three Cancer Cell Lines, as Measured Using the MTT Assay.

compound	A549	HepG2	HCT-116	MCF-7
compound	IC₅₀ (μg/mL)	IC₅₀ (μg/mL)	IC₅₀ (μg/mL)	IC₅₀ (μg/mL)
5a	ND^a	ND^a	ND^a	ND^a
5b	48.2 ±1.8	ND^a	15.5 ± 2.1	34.5 ± 2.3
5c	ND^a	ND^a	ND^a	54.6 ± 3.5
5d	71.5 ± 2.3	60.3 ± 7.9	41.6 ± 2.0	48.4 ± 2.1
5e	16.1 ± 3.1	13.8 ± 1.0	14.2 ± 0.3	12.9 ± 0.3
5f	6.9 ± 0.6	10.5 ± 0.3	3.9 ± 0.4	16.1 ± 1.5
5g	9.4 ± 7.2	15.2 ± 1.8	13.1 ± 1.2	19.1 ± 0.7
5h	1.6 ± 0.6	3.8 ±0.3	1.9 ± 0.4	1.2 ± 0.5
5i	9.7 ± 3.3	11.0 ± 0.2	7.9 ± 0.3	15.8 ± 0.7
5j	18.2 ± 1.8	20.2 ± 0.9	15.5 ± 0.2	24.5 ± 2.3
5k	12.2 ± 1.5	13.2 ± 0.9	10.5 ± 2.1	18.2 ± 2.3

ND not active.

Table 1. IC50 Values of the Derivatives in Three Cancer Cell Lines, as Measured Using the MTT Assay.