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. 2020 Jun 24;5(26):15777–15782. doi: 10.1021/acsomega.9b03574

Table 1. IC50 (mol/L) Comparison Between 5-FU and 5-FU-NCM on Tumor Cellsa.

cell lines 5-FU 5-FU-NCM
HCT116 3.25 × 10–8 ± 1.18 × 10–8 1.03 × 10–8 ± 1.34 × 10–9
HeLa 7.96 × 10–6 ± 2.13 × 10–6 1.59 × 10–6 ± 1.35 × 10–7
Hep G2 3.86 × 10–6 ± 5.56 × 10–7 3.43 × 10–6 ± 2.42 × 10–6
JEG3 2.18 × 10–6 ± 2.81 × 10–6 4.44 × 10–7 ± 2.60 × 10–7
SMMC7721 1.89 × 10–5 ± 1.58 × 10–6 6.27 × 10–8 ± 3.41 × 10–7
a

The same molar concentration of API (5-FU) was applied to a variety of cell lines in different forms: 5-FU and 5-FU-NCM.