Table 1. IC50 (mol/L) Comparison Between 5-FU and 5-FU-NCM on Tumor Cellsa.
cell lines | 5-FU | 5-FU-NCM |
---|---|---|
HCT116 | 3.25 × 10–8 ± 1.18 × 10–8 | 1.03 × 10–8 ± 1.34 × 10–9 |
HeLa | 7.96 × 10–6 ± 2.13 × 10–6 | 1.59 × 10–6 ± 1.35 × 10–7 |
Hep G2 | 3.86 × 10–6 ± 5.56 × 10–7 | 3.43 × 10–6 ± 2.42 × 10–6 |
JEG3 | 2.18 × 10–6 ± 2.81 × 10–6 | 4.44 × 10–7 ± 2.60 × 10–7 |
SMMC7721 | 1.89 × 10–5 ± 1.58 × 10–6 | 6.27 × 10–8 ± 3.41 × 10–7 |
The same molar concentration of API (5-FU) was applied to a variety of cell lines in different forms: 5-FU and 5-FU-NCM.