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. 2020 Jun 24;5(26):15777–15782. doi: 10.1021/acsomega.9b03574

Table 4. Acute Toxicity Test Result of 5-FUa.

group dose (mg/kg)/(mmol/kg) Ni Nd R (%) lg dose probit (P + 5)
1 158.5/1.22 10 9 90 2.200 6.28
2 133.4/1.03 10 7 70 2.125 5.520
3 122.2/0.86 10 1 10 2.050 3.720
a

The LD50 was 1.00 mmol/kg; 95% confidence interval is 0.38 ≤ LD50 ≤ 2.63 mmol/kg. R = Nd/Ni. Ni represents the initial animal number, while Nd represents the number of dead animals.