Table 4. Acute Toxicity Test Result of 5-FUa.
group | dose (mg/kg)/(mmol/kg) | Ni | Nd | R (%) | lg dose | probit (P + 5) |
---|---|---|---|---|---|---|
1 | 158.5/1.22 | 10 | 9 | 90 | 2.200 | 6.28 |
2 | 133.4/1.03 | 10 | 7 | 70 | 2.125 | 5.520 |
3 | 122.2/0.86 | 10 | 1 | 10 | 2.050 | 3.720 |
The LD50 was 1.00 mmol/kg; 95% confidence interval is 0.38 ≤ LD50 ≤ 2.63 mmol/kg. R = Nd/Ni. Ni represents the initial animal number, while Nd represents the number of dead animals.