Figure 2.

(A) Schematic illustration of injectable hydrogels in localized therapeutic agents’ delivery. It shows the required physical characteristics of the primary sol and as-injected gel for an ideal localized drug delivery depot. (B) Design and chemical composition of methacryloyl-substituted recombinant human tropoelastin (MeTro)/gelatin methacryloyl (GelMA)-AMP composite hydrogels. Schematic reaction of MeTro, GelMA, and AMP, after adding to TEA (co-initiator) and vinyl caprolactam (VC) (co-monomer) solutions. Eosin Y (photoinitiator) was finally introduced into the solution to become ready for spraying onto the wound area and exposing to visible light. Adapted with permission from Annabi et al. [69].