Table 1.
Patient Characteristics.
| Characteristics | Age < 70 (n = 83) |
Age ≥ 70 (n = 40) |
p-Value |
|---|---|---|---|
| ECOG (%) | 0.04 | ||
| 0–2 | 81 (97.6) | 35 (87.5) | |
| 3–4 | 2 (2.4) | 5 (12.5) | |
| Pathology (%) | 0.85 | ||
| SCC | 72 (86.7) | 36 (90) | |
| Adenosquamous carcinoma | 1 (1.2) | 0 (0) | |
| Adenocarcinoma | 9 (10.8) | 3 (7.5) | |
| Small cell carcinoma | 1 (1.2) | 1 (2.5) | |
| FIGO stage (%) | 0.75 | ||
| IA | 0 (0) | 1 (2.5) | |
| IB | 0 (0) | 0 (0) | |
| IIA | 3 (3.6) | 1 (2.5) | |
| IIB | 47 (56.6) | 20 (50) | |
| IIIA | 3 (3.6) | 2 (5) | |
| IIIB | 17 (20.5) | 8 (20) | |
| IVA | 4 (4.8) | 4 (10) | |
| IVB | 9 (10.8) | 4 (10) | |
| Total RT dose, median (Gy) (range) |
80.4 (24–106.4) |
70.3 (23.4–96) |
0.002 |
| EBRT volume | 0.06 | ||
| Tumor only | 3 (3.6) | 6 (15) | |
| Tumor and involved regions | 80 (96.4) | 34 (85) | |
| ICRT application | <0.001 | ||
| Present | 58 (69.9) | 13 (32.5) | |
| Absent | 25 (30.1) | 27 (67.5) | |
| CCRT | <0.001 | ||
| CCRT | 74 (89.2) | 21 (52.5) | |
| RT alone | 9 (10.8) | 19 (47.5) | |
| OTT of RT, median (day) | 68 | 62 | 0.35 |
Abbreviations: ECOG—Eastern Cooperative Oncology Group Performance Status, SCC—squamous cell carcinoma, FIGO—International Federation of Gynecology and Obstetrics, RT—radiotherapy, EBRT—external beam radiotherapy, ICRT—intracavitary brachytherapy, CCRT—concurrent chemoradiotherapy, OTT—Overall treatment time.