Table 3.
The list of human disease related miRNAs derived from transposable element. The coordinates of miRNAs derived from TE in the human genome, the type and name of TE that miRNAs are derived from related disorders and the references are shown in each column.
| microRNA | Coordinates | Type of TE | Related Disorders | References | |
|---|---|---|---|---|---|
| 1 | miRNA-28 | chr3:188,688,781-188,688,866 | LINE_L2c, L2c | OC, M | [74] |
| 2 | miRNA-95 | chr4:8,005,301-8,005,381 | LINE_L2b, L2c | OC, BrC | [74] |
| 3 | miRNA-130a | chr11:57,641,198-57,641,286 | LINE_MamRTE1 | LuC, OC, LiC | [46,48,75,76] |
| 4 | miRNA-151a | chr8:140,732,564-140,732,653 | LINE_L2c | G, OC, BrC, M | [49,74] |
| 5 | miRNA-151b | chr14:100,109,419-100,109,514 | LINE_L2b | OC, BrC, M | [74] |
| 6 | miRNA-181c | chr19:13,874,699-13,874,808 | LINE_MamRTE1 | LiC, A, OC, BrC | [74,77] |
| 7 | miRNA-224 | chrX: 151,958,578-151,958,658 | DNA_MER135 | LiC | [48,51] |
| 8 | miRNA-320d-1 | chr13:40,727,816-40,727,887 | LINE_L1MEd | OC, BrC, M, N | [47,48,74] |
| 9 | miRNA-335 | chr7:130,496,111-130,496,204 | SINE_MIRb | OC, M | [74] |
| 10 | miRNA-340 | chr5:180,015,303-180,015,397 | DNA_MARNA | OC | [74] |
| 11 | miRNA-342 | chr14:100,109,655-100,109,753 | SINE_MamSINE1 | EC, ACC, PaC | [48,78] |
| 12 | miRNA-361 | chrX: 85,903,636-85,903,707 | DNA_MER5A | LuC | [52] |
| 13 | miRNA-378a | chr5:149,732,825-149,732,890 | SINE_MIRc, MIRc | BlC | [49] |
| 14 | miRNA-378b | chr3:10,330,229-10,330,285 | SINE_MIR3, MIRc | L | [49] |
| 15 | miRNA-421 | chrX:74,218,377-74,218,461 | LINE_L2c, L2c | Ph, Pa | [49] |
| 16 | miRNA-513a-1 | chrX:147,213,463-147,213,591 | DNA_MER91C | LuC | [79] |
| 17 | miRNA-513a-2 | chrX:147,225,826-147,225,952 | DNA_MER91C | LuC | [79] |
| 18 | miRNA-518d | chr19:53,734,877-53,734,963 | LINE_MamRTE1 | LuC | [79] |
| 19 | miRNA-545 | chrX:74,287,104-74,287,209 | LINE_L2c | LuC | [79] |
| 20 | miRNA-546b | chr6:119,069,022-119,069,167 | DNA_MADE1 | LuC | [79] |
| 21 | miRNA-548l | chr11:94,466,495-94,466,580 | DNA_MADE1 | LuC | [79] |
| 22 | miRNA-548m | chrX:95,063,141-95,063,226 | DNA_MADE1 | LuC | [79] |
| 23 | miRNA-625 | chr14:65,471,102-65,471,186 | LINE_L1MCa | M, GC, CoC, LuC, KC | [49,80,81] |
| 24 | miRNA-626 | chr15:41,691,585-41,691,678 | LINE_L1MB8, L1MB8 | HPV | [82] |
| 25 | miRNA-646 | chr20:60,308,474-60,308,567 | LTR_LTR67B | LuC | [79] |
| 26 | miRNA-659 | chr22:37,847,678-37,847,774 | DNA_Arthur1B | D | [77] |
| 27 | miRNA-1290 | chr1:18,897,071-18,897,148 | DNA_Tigger4a | LuC | [79] |
| 28 | miRNA-1294 | chr5:154,347,071-154,347,283 | SINE_MIRb | LuC | [79] |
| 29 | miRNA-2355 | chr2:207,109,987-207,110,073 | LINE_MamRTE1, MamRTE1 | HPV | [82] |
| 30 | miRNA-1304 | chr11:93,733,674-93,733,764 | SINE_AluJo | LuC, Pr, UCEC | [50,83] |
| 31 | miRNA-3144 | chr6:120,015,179-120,015,257 | LINE_L1MA8 | LiC PrC, CeC, HPV | [82,83] |
| 32 | miRNA-3681 | chr2:12,199,130-12,199,201 | LTR_LTR16D1 | CeC, LiC | [49] |
| 33 | miRNA-4662a | chr8:124,821,985-124,822,051 | LINE_L1ME4b | LuC | [49] |
| 34 | miRNA-6503 | chr11:60,209,071-60,209,156 | LINE_MLT1D | LiC, L | [49,83] |
Abbreviations: Ovarian cancer (OC), Melanoma (M), Breast cancer (BrC), Lung cancer (LuC), Glioblastoma (G), Alzheimer (A), Neuroblastoma (N), Endocrine cancer (EC), Acrinar cell carcinoma (ACC), Pancreatic cancer (PaC), Bladder cancer (BlC), Leukemia (L), Pheochromocytoma (Ph), Paraganglioma (Pa), Gastric cancer (GC), Colorectal cancer (CoC), Kidney cancer (KC), Human papillomavirus (HPV), Dementia (D), Preeclampsia (Pr), Uterine Corpus Endometrial Carcinoma (UCEC), Prostate cancer (PrC), Cervical cancer (CeC), Liver cancer (LiC).