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Function of circRNAs. (a) circRNAs competitively bind with miRNA which results in less mRNA degradation or translation inhibition. (b) circRNAs interact with RBPs to influence GC progression. (c) circRNAs interact with pol II and U1snRNP to regulate transcription and splicing. (d) circRNAs which encode proteins rely on the IRES-dependent or m6a-dependent translation initiation.
