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. 2020 Jun 4;12(11):10873–10895. doi: 10.18632/aging.103301

Figure 10.

Figure 10

Downregulation of miR-137 increases oxidative stress and inflammatory response in brain tissues from MCAO mice. (A) ROS content in brain tissues from miR-137-/- mice after staining with a DCFH-DA fluorescently-labeled probe; (B) TNF-α, IL-1, IL-6, IL-17 and IL-10 expression in brain tissues from miR-137-/- mice using ELISA. Data are expressed as mean ± standard deviation and compared by one-way ANOVA, followed by Tukey's post hoc test. * p < 0.05 vs. control group (sham-operated wild-type mice); # p < 0.05 vs. MCAO group (wild-type mouse models of MCAO). N = 15.