Table 4. Soluble FAP (sFAP) levels according to clinical and pathological parameters of CRC patients.
| Patients’ clinical and pathological data (n=127) | Average (%) | sFAP levels (ng/ml) | p value | |
| Follow-up months (range) | 50 (3-83) | |||
| Age average (range) | 70 (34-93) | |||
| Gender | Male | 92 (72%) | 57.9 | 0.61 |
| Female | 35 (28%) | 60.1 | ||
| Histologic grade (G) | G1 | 6 (5%) | 57.4 | 0,92 |
| G2 | 118 (93%) | 58.7 | ||
| G3 | 3 (2%) | 53.7 | ||
| Local invasion (pT) | pT2 | 32 (25%) | 60.3 | 0.41 |
| pT3 | 85 (67%) | 58.9 | ||
| pT4 | 10 (8%) | 50.1 | ||
| Affected lymph nodes (N) | N0 | 75 (59%) | 60.2 | 0.41 |
| N1 | 41 (32%) | 57.4 | ||
| N2 | 11 (9%) | 51.4 | ||
| Distant metastases (M) | M0 | 123 | 58.4 | 0.75 |
| M1 | 4 | 61.9 | ||
| Stage (TNM system) | I | 26 (20%) | 56.9 | 0.29 |
| II | 48 (38%) | 62.9 | ||
| III | 49 (39%) | 54.8 | ||
| IV | 4 (3%) | 61.9 | ||
| Blood vessel invasion (V) | No | 110 (87%) | 58.6 | 0.97 |
| Yes | 17 (13%) | 58.3 | ||
| Lymphatic vessel invasion (L) | No | 103 (81%) | 60.6 | 0.03 |
| Yes | 24 (19%) | 49.8 | ||
| Perineural invasion (Pn) | No | 108 (85%) | 58.5 | 0.99 |
| Yes | 19 (15%) | 58.7 | ||
T Student test and ANOVA test were used for the comparison between two or more than two groups respectively. Significant p values are highlighted in bold.