Table 1. Study population comorbidities.

Comorbidities	O-IN (N = 14) (N, %)	P-IN (N = 24) (N, %)	q value
Cardiovascular disorders (rhythm disturbances, flutter)	3 (21%)	4 (17%)	1
Endocrine disturbances (hypothyroidism/hyperthyroidism, insulin resistance, metabolic syndrome, hyperuricemia)	5 (36%)	10 (43%)	1
Musculoskeletal system syndromes (arthrosis, osteoporosis, fibromyalgia)	7 (50%)	20 (87%)	1
Vascular disorders (hypertension, venous insufficiency)	5 (36%)	11 (48%)	1
Dyslipidemia	0 (0%)	11 (48%)	0.2
Chronic respiratory diseases (asthma/chronic obstructive pulmonary disease)	1 (7%)	3 (13%)	0.9
Autoimmune disorders (Raynaud’s syndrome, Hashimoto)	1 (7%)	1 (4%)	1
Gastrointestinal disturbances (gastroesophageal reflux, gastritis)	2 (14%)	3 (13%)	1

The comparison between the two groups of patients (O-IN versus P-IN) was performed by using two-sided Mann-Whitney test with Benjamini-Hochberg correction, considering q (corrected p-value) <0.05 statistically significant (*). No significant difference emerged between the two groups of patients.

O-IN = Objective Insomnia patients. P-IN = Paradoxical Insomnia patients.